Antibodies are the body’s innate response to custom monoclonal antibodies for targetted research, binding to them via a lock-and-key mechanism and thereby pacifying them. They are critical in most biological applications as they can be used to purify, detect and identify specific substances. Originally derived from the immune system, these antibodies offer unparalleled accuracy and precision that conventional research reagents cannot match. Custom monoclonal antibodies can be produced to target a particular epitope of interest, providing the perfect tool for your targetted research.

Our comprehensive range of custom monoclonal antibody services offers high-quality, highly-specific and reliable results for your most challenging targets. Using a variety of methods, our experts create monoclonal antibodies that can be used for Western blot, immunofluorescence, cell-based screening and IHC. We also offer a range of antibody characterization and screening services to support your research.

Protein Expression Services: How Custom Solutions Improve Lab Efficiency

Custom monoclonal antibody production is performed using hybridoma technology, which consists of immunizing an animal with a mixture of different proteins and cells that will stimulate the immune system’s production of antibodies. Once the desired antibodies are present in the animal’s serum, they are collected and fused with myeloma cells in a process called fusion selection, which identifies the resulting hybridoma cells that produce high-quality monoclonal antibodies.

These mAbs are then subjected to at least two rounds of limiting dilution cloning to establish chromosomally stable monoclonal antibody-producing cell lines. The final mAbs are then stored in dedicated liquid nitrogen tanks for long-term preservation and provided to the client in a format suitable for most in vitro applications.…